Drug Discovery Research Screening Libraries
AdipoGen TEPP46 ML-265
Chemical. CAS 1221186-53-3. Formula C17H16N4O2S2. MW 372.5. . Potent and selective cell-permeable pyruvate kinase M2 PKM2 activator with little or no activity versus PKM1, PKL and PKR. Useful agent for immunometabolism research. Anticancer reducing tumor sizes in mice and anti-inflammatory agent. Shown to bind the enzyme PKM2 to promote formation of stable, enzymatically-active tetramers, thereby promoting the last rate-limiting step of glycolysis, converting PEP to pyruvate. In addition, it prevents PKM2 translocation to the nucleus resulting in reduced glycolysis and HIF-1alpha activation, causing diminished Warburg effect and IL-1beta production.
AdipoGen Linagliptin
Chemical. CAS 668270-12-0. Formula C25H28N8O2. MW 472.5. Antidiabetic agent. Highly potent and selective competitive inhibitor of dipeptidyl-peptidase 4 DPP4 DPP IV CD26, an enzyme that degrades, glucagon-like peptide-1 GLP-1 and glucose-dependent insulinotropic polypeptide GIP. Prevents the inactivation of endogenous GLP-1 and GIP. Shown to restore beta cell function and survival in human isolated islets through GLP-1 stabilization. Improves insulin sensitivity. Anti-inflammatory compound.
AdipoGen UK 5099
Chemical. CAS 56396-35-1. Formula C18H12N2O2. MW 288.3. . Potent and specific inhibitor of the mitochondrial pyruvate carrier MPC, blocking pyruvate from entering the mitochondria, consequently promoting lactate production. Inhibitor of tricarboxylic acid TCA cycle. Plasma membrane monocarboxylate transporters MCTs inhibitor, but with Ki values some two or three orders of magnitude higher than those for the inhibition of the MPC. Inhibits mitochondrial lactate and pyruvate transport. Decreases glycolysis. Useful agent for immunometabolism research.
OBORO LABS INC CAS# 1007375-08-7. 250 mg. OCO-Me Pincer Ligand, 99%. IUPAC Name: 1,1′:3′,1′′-Terphenyl, 3,3′′-bis(1,1-dimethylethyl)-2,2′′-dimethoxy-
CAS# 1007375-08-7. 250 mg. OCO-Me Pincer Ligand, 99%. IUPAC Name: 1,1′:3′,1′′-Terphenyl, 3,3′′-bis(1,1-dimethylethyl)-2,2′′-dimethoxy-
Apexbio Technology LLC DiscoveryProbe™ NF-B Signaling Library, 250uL/well(10 mM solution), 96 Well Racks With Screw Cap
A unique collection of 73 NF-B inhibitors for NF-B signaling pathway research. Other sizes are available. Please inqury us for quote.
AdipoGen bpVphen
Chemical. CAS 171202-16-7. Formula KVOO22C12H8N2 . 3H2O. MW 350.2 . 54.0. Potent protein phosphotyrosine phosphatase inhibitor. Insulin receptor kinase IRK inducer. Insulin mimetic in vitro and in vivo. Apoptosis inducer. ERK inducer. Mitogen-activated protein kinase phosphatase-1 MKP-1 inducer. Angiogenesis inhibitor. PTEN inhibitor.
![OBORO LABS INC CAS# 1007375-02-1. 250 mg. OCOH3 Pincer Ligand, 99%. IUPAC Name: 2,2',2''-(1,1-Dimethylethylidene)tris[1,1'-biphenyl]-4,4'-diol](https://assets.fishersci.com/TFS-Assets/CCG/product-images/Oboro2.jpg-250.jpg)
OBORO LABS INC CAS# 1007375-02-1. 250 mg. OCOH3 Pincer Ligand, 99%. IUPAC Name: 2,2',2''-(1,1-Dimethylethylidene)tris[1,1'-biphenyl]-4,4'-diol
CAS# 1007375-02-1. 250 mg. OCOH3 Pincer Ligand, 99%. IUPAC Name: 2,2',2''-(1,1-Dimethylethylidene)tris[1,1'-biphenyl]-4,4'-diol
OBORO LABS INC CAS# 1007375-08-7. 100 g. OCO-Me Pincer Ligand, 99%. IUPAC Name: 1,1′:3′,1′′-Terphenyl, 3,3′′-bis(1,1-dimethylethyl)-2,2′′-dimethoxy-
CAS# 1007375-08-7. 100 g. OCO-Me Pincer Ligand, 99%. IUPAC Name: 1,1′:3′,1′′-Terphenyl, 3,3′′-bis(1,1-dimethylethyl)-2,2′′-dimethoxy-
OBORO LABS INC CAS# 1007375-02-1. 100 g. OCOH3 Pincer Ligand, 99%. IUPAC Name: 2,2',2''-(1,1-Dimethylethylidene)tris[1,1'-biphenyl]-4,4'-diol
CAS# 1007375-02-1. 100 g. OCOH3 Pincer Ligand, 99%. IUPAC Name: 2,2',2''-(1,1-Dimethylethylidene)tris[1,1'-biphenyl]-4,4'-diol
Selleck Chemical LLC Anti-cancer Compound Library 100uL/well
A unique collection of 3547 anti-cancer compounds for multiple cancers: Breast Cancer, Leukemia, Lung Cancer, Lymphoma, etc. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Autophagy Compound Library 100uL/well
A unique collection of 1029 small molecules with autophagy-inducing or autophagy-inhibiting activity. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Abcam TG x -221, PI3K inhibitor, 500UG
MW 364.45 g/mol, Purity >98%. TGX-221, PI3K inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement